Reproductive Environment in Patients with SLE
By María del Carmen Zamora Medina, Andrea Hinojosa Azaola, Carlos A. Núñez Alvarez, Angel Gabriel Vargas Ruiz and Juanita Romero Díaz
Submitted: December 12th 2018
Reviewed: February 22nd 2019
Published: April 9th 2019
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This Article in Multisystemic Autoimmune Disorder was written along with my fellowmates Andrea Hinojosa Azaola, Carlos A. Núñez Alvarez, Angel Gabriel Vargas Ruiz and Juanita Romero-Díaz back in December 2018 while we were at service in Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán in Mexico City.
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder that predominantly affects women in reproductive years. Immunologic and hormonal adaptations during pregnancy focused on creating an ideal environment to achieve a successful pregnancy represent a challenge in SLE women as they can influence on disease activity and outcomes during pregnancy.
Several disease-related factors such as the presence of antiphospholipid antibodies and anti-SSA/Ro can also impact in the risk of pregnancy adverse outcomes and neonatal complications.